Long-Read RNA Isoform Sequencing

Power your RNA isoform discovery with high-throughput technology for robust isoform and fusion identification.

Reveal Complete Transcriptomes with Advanced Long-Read Isoform Sequencing Solutions

Overcome the throughput barriers that limit traditional long-read RNA sequencing and prevent comprehensive transcriptome characterization. Broad Clinical Labs’ Long-Read RNA Isoform Sequencing delivers unmatched sequencing depth and coverage using the pioneering Multiplexed Arrays Isoform Sequencing (MAS-seq) approach with PacBio’s Kinnex™ Full-Length RNA kit.

Experience the most complete and accurate full-length RNA sequencing data available—maximizing biological insights while minimizing experimental complexity.

Full-Length RNA Sequencing Service

Leveraging PacBio’s Kinnex/MAS-seq technology, our workflow boosts throughput eightfold by concatenating full-length cDNAs into optimized arrays. Each array handles up to 12 samples and generates 30–50 million high-quality reads, enabling robust identification of full-length RNA isoforms, fusions, and alternative splicing events.

Assembly-Free Accuracy with Kinnex Technology

Accurate isoform identification poses a significant challenge in transcriptome analysis. Traditional short-read RNA sequencing fragments cDNAs and relies on computational assembly, often producing inaccurate results due to complex alternative splicing. The MAS-seq approach of the Kinnex full-length RNA kit eliminates assembly entirely by sequencing complete transcripts end-to-end for unambiguous isoform identification.

Long-Read RNA Sequencing Benefits That Unravel Transcriptomic Complexities

Accelerated Discovery Timelines

The exceptional sequencing efficiency of MAS-seq technology accelerates research cycles with 8-fold higher throughput for faster, more detailed transcriptome analysis.

Unprecedented Accuracy

Eliminate the uncertainty of transcript assembly with full-length sequencing that provides unambiguous isoform identification.

Maximum Transcriptome Insights

Achieve unparalleled sequencing depth and coverage essential for understanding complex transcriptome dynamics.

End-to-End Simplicity

Our streamlined service handles the complete workflow, from sample processing and library construction through secure cloud-based data delivery.

Diverse Applications of Long-Read RNA Isoform Sequencing

Leverage the unmatched accuracy of full-length transcript sequencing to advance research across multiple disciplines.

Disease Research & Biomarker Discovery

Drug Discovery & Development

Genomic Annotation & Gene Discovery