Biomarker Discovery and Analysis Platforms
Broad Clinical Labs is committed to supporting breakthroughs in translational and clinical research that better human health. Our comprehensive biomarker discovery platform covers insights from common point mutations to intricate gene expression profiles, enabling both exploratory and targeted biomarker research across preclinical and population cohorts.
Applications of Biomarker Research and Discovery
Drug Discovery: Identifying new drug targets and biomarkers for therapeutic development.
Clinical Trials: Validating biomarkers and stratifying patients.
Precision Medicine: Developing personalized treatments based on individual genetic profiles.
Disease Diagnosis and Prognosis: Improving early detection and predicting disease outcomes.
Population Health: Understanding disease prevalence and risk factors within specific populations.
Types of Biomarkers
Sequencing Solutions for Biomarker Discovery and Research
We offer sequencing services to power every stage of the drug development pipeline and to complement a diverse set of research and clinical applications. Learn more about our relevant services, and reach out to our team for personalized recommendations. We scale our sequencing services to meet the needs of your project and offer analytical support from start to finish.
Comprehensive Sequencing Services
Whole Genome Sequencing
• Treatment response biomarkers
• Research Short-read, Research Long-read, and Clinical Short-read available
Blended Genome-Exome Sequencing
• Research and Clinical BGE available
RNA Sequencing
• Whole Transcriptome, Total RNA, and Transcriptome Capture available
Plasma Proteomic Profiling
• Olink® Explore HT assay available
Whole Exome Sequencing
• Homologous recombination repair deficiency
• Microsatellite instability
• Research germline, Research somatic, and Clinical somatic available
Single Cell Sequencing
• Monitoring biomarkers of drug response and disease progression
• 10x Single Cell Gene Expression (3' or 5'), 10x Genomics Single Cell Multiome, and SmartSeq2 available
Whole Genome Sequencing
• Treatment response biomarkers
• Research Short-read, Research Long-read, and Clinical Short-read available
Blended Genome-Exome Sequencing
• Research and Clinical BGE available
RNA Sequencing
• Whole Transcriptome, Total RNA, and Transcriptome Capture available
Plasma Proteomic Profiling
• Olink® Explore HT assay available
Whole Exome Sequencing
• Homologous recombination repair deficiency
• Microsatellite instability
• Research germline, Research somatic, and Clinical somatic available
Single Cell Sequencing
• Monitoring biomarkers of drug response and disease progression
• 10x Single Cell Gene Expression (3' or 5'), 10x Genomics Single Cell Multiome, and SmartSeq2 available
Whole Genome Sequencing
- Novel prognostic/diagnostic biomarkers
- Treatment response biomarkers
- Research Short-read, Research Long-read, and Clinical Short-read available
Blended Genome-Exome Sequencing
- Low-pass WGS and deep WES combined for integrated insights
- Research and Clinical BGE available
RNA Sequencing
- Gene expression, alternative transcripts or splicing events
- Whole Transcriptome, Total RNA, and Transcriptome Capture available
Plasma Proteomic Profiling
- Protein biomarkers: inflammatory, organ-specific, drug targets
- Olink® Explore HT assay available
Whole Exome Sequencing
- Tumor mutational burden
- Homologous recombination repair deficiency
- Microsatellite instability
- Research germline, Research somatic, and Clinical somatic available
Single Cell Sequencing
- Biomarkers for patient stratification
- Monitoring biomarkers of drug response and disease progression
- 10x Single Cell Gene Expression (3' or 5'), 10x Genomics Single Cell Multiome, and SmartSeq2 available
Advanced Data Analysis:
- Cutting edge analytical techniques from the Methods Development Lab (e.g. isoform sequencing)
- Easily accessible, standardized bioinformatic pipelines and tools
- Collaborative results delivery and interpretation
Quality Assurance and Control:
- Rigorous quality control measures
- Laboratory CLIA Licensure and CAP Accreditation
- Backed by 30+ years of expertise in the Broad community and beyond
Benefits of Partnering with
Broad Clinical Labs
Full-service platform:
We support multiomic projects from conception to clinical implementation.
High-quality data:
Accurate and reliable results for your research.
Timely delivery:
Rapid turnaround times to accelerate your projects.
Expertise:
Access to a team of experienced scientists and technicians.
Scalability:
High-throughput solutions to meet your specific needs.
Read More
About Our Biomarker Research
Learn more about BCL-powered research, including biomarker discovery, on our Resources page.
Ready to get started?
See our full list of services to find the right one for your project
