Clinical Whole Genome Sequencing
Comprehensive whole genome sequencing that delivers high-quality, reliable data for your downstream bioinformatic analysis.
Power Clinical Research with Whole Genome Sequencing
Breakthroughs in translational research require comprehensive whole genome sequencing that captures the full spectrum of genetic variation—but accessing clinical-grade data often means compromising on cost or quality. Broad Clinical Labs eliminates this trade-off with Clinical Whole Genome Sequencing (WGS) services that deliver cost-effective, scalable solutions at rigorous quality standards, enabling CLIA-certified entities to interpret and report results in distributed testing models.
With validated processes proven across 850,000+ genomes sequenced, our Clinical WGS is backed by expert support to advance your clinical genomic programs.
PCR-Free Short Read Clinical WGS
starting at $499
Leverage PCR-free whole genome sequencing for comprehensive variant detection across coding and non-coding regions. High-depth coverage from our CLIA-licensed and CAP-accredited facility enables sensitive detection of SNVs, InDels, structural variants, and copy number alterations—delivering superior data quality and consistency to empower confident bioinformatic analysis.
Accelerate Clinical Programs with Industry-Leading Whole Genome Sequencing
Clinical Applications
High-quality whole genome sequencing that supports breakthroughs across the clinical genomics spectrum.
Translational Genomics
- Clinical cohort genomic analysis
- Disease mechanism characterization
- Genetic risk factor identification
Precision Medicine Initiatives
- Treatment response prediction
- Pharmacogenomics research
Rare Disease Characterization
- Variant pathogenicity evaluation
- Novel variant identification
- Gene-disease studies
Clinical Whole Genome Sequencing with Broad Clinical Labs
| Service Type | Data Deliverables | What’s Included |
|---|---|---|
|
PCR-free Short Read Clinical WGS on Illumina® NovaSeq X Plus |
CRAM, VCF, and technical report (pdf) |
|
Project Workflow- Clinical Whole Genome Sequencing
Project onboarding
(contracting if required)
Regulatory Review
Quoting
Sample Kits
Sample intake and QC
(extraction optional)
Whole blood, buccal swab, saliva, buffy coat, DNA
Library construction
PCR-Free
Sequencing
Illumina® NovaSeq X Plus
Data and report delivery
(bioinformatic analysis optional)
Data analysis using Illumina® DRAGEN™ analytical pipeline.
Data delivered via secure cloud-based platform.
Project onboarding
(contracting if required)
Regulatory Review
Quoting
Sample Kits
Sample intake and QC
(extraction optional)
Whole blood, buccal swab, saliva, buffy coat, DNA
Library construction
PCR-Free
Sequencing
Illumina® NovaSeq X Plus
Data and report delivery
(bioinformatic analysis optional)
Data analysis using Illumina® DRAGEN™ analytical pipeline.
Data delivered via secure cloud-based platform.
Partnerships & Landmark Projects
Our 30 years of genomic sequencing expertise, combined with our commitment to furthering genomic science, has enabled strategic partnerships and project contributions that drive global impact and advancements in human health research.
Human Genome Project
Data generated by our Genomics Platform service enabled the success of the landmark Human Genome Project, a project that continues to drive genomic discovery today.
gnomAD
We helped contribute to the largest public resource of human genetic variation data, enabling researchers to interpret genetic variants and advance precision medicine.
NHLBI TOPMed
Our role in the NHLBI TOPMed initiative facilitated the generation of whole genome data that has advanced the understanding of heart, lung, blood, and sleep disorders across diverse populations.
1000 Genomes Project
Our sequencing services helped create the comprehensive catalog of human genetic variation that serves as a cornerstone reference for population genetics research worldwide.
NIH All of Us
As part of the NIH All of Us Research Program, we’re helping create a revolutionary cloud-based platform of genomic data from one million diverse volunteers, creating a democratized resource to accelerate precision medicine research.